The site's owner, Canadian Gary Fung, has agreed to pay $110m (£68m) to the Motion Picture Association of America (MPAA).
MPAA chairman Chris Dodd said the move was a "major step forward" for legitimate commerce online.
In a blog post, Mr Fung said: "It's sad to see my baby go."
The site is currently still online, but will soon be shut. It is one of the most popular sites of its kind on the internet.
This is it. We are shutting down isoHunt services a little early. I'm told there was this Internet archival team that wants to make historical copy of our .torrent files, I'm honoured that people think our site is worthy of historical preservation. But the truth is about 95% of those .torrent files can be found off Google regardless and mostly have been indexed from other BitTorrent sites in the first place. So I might as well do a proper send-off to you dear isoHunt users, before final shutdown sequence on Tuesday. It's been an adventure in the last 10.5 years working on isoHunt, a privilege working with some of the smartest guys I've worked with, and my life won't be the same without this journey. For what I'm working on next, please look up my blog on Google and follow me there. Because as the Terminator would say with a German accent,
I'll be back.
- Gary Fung
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